| Monica Saenz | | Director of Gear Up Grant | | Gear Up |
| Claudia Sailler | | Advancement Coordinator | | Office of Development & Advancement |
| Bushra Sajid | | Assistant Professor of Computer Science | | Computer, Mathematical and Physical Sciences |
| Mark Saka | | RGC Professor History | | Behavioral & Social Sciences |
| Jesse Salazar | | Assistant Professor | | Education |
| Christa Saldaris, PhD, MSN, RN, CEN | | Faculty Part Time NS | | Nursing |
| Roberto Sanchez Gandara | | Custodial Worker | | Physical Plant |
| Corey Sanders | | Faculty Part Time NS | | Industrial Technology |
| Jawanna Sanderson | | Assistant Professor of Accounting | | Business Administration |
| Ruben Sandoval | | Faculty Part Time NS | | Behavioral & Social Sciences |
| Rachel Sangster Garza | | Visiting Assistant Professor of Spanish | | Languages & Literature |
| Cody Santos | | | | Computer Science & Mathematics |
| Mary Jane Sauceda | | Associate Professor of Accounting | | Business Administration |
| Christopher Schaefer | | | | Criminal Justice |
| Jessica Schauman | | Coordinator of Academic Affairs | | Academic Affairs |
| Joseph Schmiedehaus | | Faculty Part Time NS | | Behavioral & Social Sciences |
| Jared Schniers | | Project Coordinator Alamito Creek Conservation Initiative | | Borderlands Research Institute |
| Beverly Schonhoff, Ph.D | | Faculty Part Time NS | | Education |
| Bryon Schroeder | | Senior Research Scientist for CBBS | | Center for Big Bend Studies |
| Allison Scott | | Instructor | | Behavioral & Social Sciences |
| Bret Scott, MFA | | Assoc. Professor of Cinema Arts | | Fine Arts & Communication |
| Marjorie Scott | | Chair & Associate Prof Comm/Theatre | | Fine Arts & Communication |
| Barbara Scown | | Faculty Part Time NS | | Computer, Mathematical and Physical Sciences |
| Ansu Sebastian | | | | Nursing |
| Prabakaran Sellamuthu | | Assistant Professor | | Business Administration-RGC |
| Sumantra Sengupta | | Dean Rio Grande College of Business | | Business Administration |
| Tonya Senne | | Faculty Part Time NS | | Education |
| Mainuddin Shaik, Ph.D. | | Interim Dept. Chair, Natural & Behavioral Sciences| Asst. Professor, CS & Cybersecurity | | Natural & Behavioral Sciences |
| Sarah Sheffield | | Information Security Specialist | | Office of Information Technology |
| Thomas Shiller | | Associate Professor Geology | | Natural Sciences |
| Glenn Short | | Instructor of Education -Alpine Campus- | | Education |
| Cynthia Sifuentes | | Project Director | | Title V Culture of Care |
| Eddie Sinegal | | University Recruiter | | Enrollment Management |
| Cynthia Slocumb | | Operations Supervisor | | Library |
| Paul Slocumb | | Administrative Specialist HR | | Human Resources |
| Edgar Smith | | Temp Monthly Finance and Operation | | Finance & Operations |
| Eun Jung Smith | | Head Women Basketball | | Athletics |
| Jadah Smith | | Senior Financial Aid Counselor | | Financial Aid |
| Helen Snook | | Borderlands Research Temp | | Borderlands Research Institute |
| Laura Sotelo | | Associate Director of Gear Up | | Gear Up |
| Jesus Spencer | | Property Manager | | Finance & Operations |
| Stanley Standly | | | | Fine Arts & Communication |
| Kathy Stein | | | | Academic Center for Excellence |
| Alyssa Stewart | | Part-time Faculty Nursing | | Nursing |
| Cody Stone | | Assistant Athletic Director for Athletic Business and Operations | | Athletics |
| Conner Sumbera | | | | Homeland Security & Criminal Justice |
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